Molecular definition of inflammasomes


Autoria(s): Pétrilli V.; Martinon F.; Couillin I. (ed.); Pétrilli V. (ed.); Martinon F. (ed.)
Data(s)

2011

Resumo

Inflammasomes are crucial actors of the innate immunity. They consist of cytoplasmic multiprotein complexes controlling the biological activities of the inflammatory cytokines IL-1ß and IL-18. Inflammasome assembly depends on protein domain interaction. In this chapter, we focus on the biochemical aspects characterizing the components of the inflammasomes and their assembly into a high moelcuar weight protelytic complex.

Identificador

http://serval.unil.ch/?id=serval:BIB_21D97121A13C

isbn:978-3-0348-0147-8

doi:10.1007/978-3-0348-0148-5

Idioma(s)

en

Publicador

Basel: Springer

Fonte

The inflammasomes

Tipo

info:eu-repo/semantics/bookPart

incollection