Monoclonal antibodies for the identification of New World Leishmania species


Autoria(s): Grimaldi Jr,Gabriel; McMahon-Pratt,Diane
Data(s)

01/02/1996

Resumo

Monoclonal antibodies specific for selected species complexes of Leishmania have been employed for the characterization of several representative strains of Leishmania isolated from different hosts and localities in the Americas. In the past 15 years, data have been accumulated concerning (i) the specificities of a number of these monoclonal antibodies and (ii) the antigenic variation (level of the expressed antigenic determinants) occurring among New World Leishmania species or strain variants as recognized by the monoclonal antibodies. This report is an attempt to summarize in brief the data accumulated to date on these points and to indicate the directions for future applications of these specific monoclonal antibodies for identification of leishmanial isolates.

Formato

text/html

Identificador

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761996000100006

Idioma(s)

en

Publicador

Instituto Oswaldo Cruz, Ministério da Saúde

Fonte

Memórias do Instituto Oswaldo Cruz v.91 n.1 1996

Palavras-Chave #Leishmania #serodemes #monoclonal antibodies #radioimmune binding assay #immunotaxonomy
Tipo

journal article