Transmission blocking immunity as observed in a feeder system and serological reactivity to Pfs 48/45 and Pfs230 in field sera


Autoria(s): Roeffen,W.; Lensen,T.; Mulder,B.; Teelen,K.; Sauerwein,R.; Eling,W.; Meuwissen,JHETh; Beckers,P.
Data(s)

01/01/1994

Resumo

Monoclonal antibodies (mAbs) and human sera from gametocyte carriers were applied in the bio-assay to test for their transmission-blocking capacity. Competition ELISA's have been developed for the detection of natural transmission blocking antibodies. Approximately 55 of the sera blocking in the bio-assay gave positive results in these competition ELISA's.

Formato

text/html

Identificador

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761994000600004

Idioma(s)

en

Publicador

Instituto Oswaldo Cruz, Ministério da Saúde

Fonte

Memórias do Instituto Oswaldo Cruz v.89 suppl.2 1994

Palavras-Chave #Plasmodium falciparum #transmission/blockade #natural antibodies #competition ELISA's
Tipo

journal article