Microcalorimetry Assay for Rapid Detection of Voriconazole Resistance in Aspergillus fumigatus.


Autoria(s): Furustrand Tafin U.; Meis J.F.; Trampuz A.
Data(s)

2013

Resumo

We describe a calorimetric assay for detection of voriconazole-resistant Aspergillus fumigatus within 8 h. Among 27 genetically distinct strains, all 21 resistant and all 6 susceptible strains were correctly identified by measurement of fungal heat production in the presence of voriconazole. This proof-of-concept study demonstrates the potential of microcalorimetry for rapid detection of azole resistance in A. fumigatus.

Identificador

https://serval.unil.ch/?id=serval:BIB_073FD22A2829

isbn:1098-6596 (Electronic)

pmid:23939893

doi:10.1128/AAC.01379-13

isiid:000325764000066

Idioma(s)

en

Fonte

Antimicrobial Agents and Chemotherapy, vol. 57, no. 11, pp. 5704-5706

Tipo

info:eu-repo/semantics/article

article