p63 and epithelial metaplasia: a gutsy choice.


Autoria(s): Lefort K.; Dotto G.P.
Data(s)

2011

Resumo

Barrett's esophagus is an epithelial metaplasia associated with an increased risk for cancer, but its underlying mechanisms have been debated. Now Wang et al. (2011) suggest an intriguing explanation for this puzzle: a population of residual embryonic cells, lacking the transcription factor p63, migrates and repopulates a normal tissue damaged by inflammation or gastroesophageal reflux.

Identificador

https://serval.unil.ch/?id=serval:BIB_03320D20688F

isbn:1097-4172 (Electronic)

pmid:21703442

doi:10.1016/j.cell.2011.06.008

isiid:000292025700005

Idioma(s)

en

Fonte

Cell, vol. 145, no. 7, pp. 1003-1005

Tipo

info:eu-repo/semantics/article

article