Magnetoliposomes based on manganese ferrite nanoparticles as nanocarriers for antitumor drugs


Autoria(s): Rodrigues, Ana Rita Oliveira; Ramos, José M. F.; Gomes, Isabel Alexandra Domingues Tarroso; Almeida, B. G.; Araújo, João P.; Queiroz, Maria João R. P.; Castanheira, Elisabete M. S.; Coutinho, Paulo J. G.
Data(s)

01/02/2016

Resumo

Publicado em "NanoPT2016 book of abstracts"

In this work, manganese ferrite (MnFe2O4) nanoparticles with superparamagnetic behaviour at room temperature and size distribution of 26 ± 5 nm, were obtained by coprecipitation method. Structural and magnetic properties of the nanoparticles (NPs) were evaluated by XRD, HR-TEM and SQUID. The synthesized NPs were either entrapped in liposomes, originating aqueous magnetoliposomes (AMLs), or covered with a lipid bilayer, forming solid magnetoliposomes (SMLs).

This work was supported by FEDER through the COMPETE/QREN/EU Program and by the Portuguese Foundation for Science and Technology (FCT) in the framework of the Strategic Projects of CFUM [PEst-C/FIS/UI0607/2013 (F-COMP-01-0124-FEDER-022711)] and CQ/UM [PEst-C/QUI/UI0686/2013 (FCOMP-01-0124-FEDER -022716)]. FCT, POPH-QREN and FSE are acknowledged for the PhD grant of A.R.O. Rodrigues (SFRH/BD/90949/2012) and for financial support to MAP-Fis PhD Programme.

Identificador

http://hdl.handle.net/1822/40847

Idioma(s)

eng

Publicador

Phantoms Foundation

Relação

http://www.nanopt.org/16Abstracts/2016_Rodrigues_Rita_ritarodrigues@fisica.uminho.pt_Abstract_NanoPt_RitaRodrigues.pdf

Direitos

info:eu-repo/semantics/openAccess

Palavras-Chave #Drug delivery #Magnetic nanoparticles #Liposomes #Cancer therapy
Tipo

info:eu-repo/semantics/conferenceObject