Evaluation of the histopathological hepatic lesions and opportunistic agents in Brazilian HIV patients
Data(s) |
01/02/2010
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Resumo |
INTRODUCTION: to evaluated the type histopathological hepatic lesions and opportunistic agents in Brazilian HIV-infected patients. METHODS: we examined 52 percutaneous liver biopsies of 50 HIV-infected patients who had at least two of the following conditions: fever of unknown origin, unexplained severe emaciation, hepatomegaly or abnormal liver chemistry. The specimens were cultured for mycobacteria and fungi and stained by standard procedures. RESULTS: reactive patterns, granulomatous hepatitis and chronic active hepatitis were verified in 28 (54%), 11 (21%) and 8 (15%) of the patients respectively. Opportunistic infections were diagnosed in 18 (36%) patients: mycobacteria in 12 (24%), Cryptococcus neoformans in 5 (10%) patients and mycobacteria and yeast was isolated from the same liver fragment in one patient. CONCLUSIONS: mycobacteriosis was the most common opportunistic infection and liver tissue culture is an important method to detect opportunistic agents, even in the absence of histological lesions. |
Formato |
text/html |
Identificador |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822010000100001 |
Idioma(s) |
en |
Publicador |
Sociedade Brasileira de Medicina Tropical - SBMT |
Fonte |
Revista da Sociedade Brasileira de Medicina Tropical v.43 n.1 2010 |
Palavras-Chave | #Liver biopsy #Mycobacteriosis #AIDS #Liver histology |
Tipo |
journal article |