Role of Yap8 and Yap1 b-ZIP transcription factors in arsenic stress


Autoria(s): Amaral, Catarina Sá Almeida
Contribuinte(s)

Rodrigues-Pousada, Claudina

Data(s)

16/01/2015

16/01/2015

01/01/2010

01/01/2015

Resumo

Arsenic compounds are highly toxic substances; nevertheless they are used in the treatment of acute promyelocytic leukaemia. Therefore it is pressing to gain knowledge on its toxicity and detoxification mechanisms. The cellular entry pathways have been discovered and by transcriptome analysis it is known that arsenic activates the transcription of genes activated by, among others, Rpn4, Met4 and Yap1.(...)

Fundação para a Ciência e a Tecnologia

Identificador

http://hdl.handle.net/10362/14119

Idioma(s)

eng

Direitos

openAccess

Tipo

doctoralThesis