Serum lipids of pemphigus foliaceus patients on long-term glucocorticoid therapy


Autoria(s): Cunha,Selma Freire de Carvalho da; Santos,Vitorino Modesto dos; Monteiro,Jacqueline Pontes; Ferreira,Tácio Pierre Sousa; Santos,Jenner Arruda Modesto dos; Santos,Taciana Arruda Modesto dos; Cunha,Daniel Ferreira da
Data(s)

01/01/2003

Resumo

Endemic pemphigus foliaceus, and long-term corticotherapy may affect serum lipid levels. The aim of this study was to compare serum lipids of pemphigus foliaceus patients on glucocorticoid therapy to a healthy control group. Fifteen patients receiving prednisone (0.33 ± 0.22mg/kg) for at least 12 months and 15 controls were submitted to 48-h food intake records, anthropometry, and biochemical measurements. Data were compared by chi2, Mann-Whitney and Student "t" tests. The groups were matched for gender, age, weight, body mass index, arm circumference and triceps skin fold. No differences were observed in relation to energy, fat, protein and carbohydrate daily intakes, total cholesterol, HDL, LDL, uric acid, and serum creatinine levels. Pemphigus foliaceus patients had higher triglyceride [159 (64-371) vs. 100 (45-133) mg/dl], VLDL [32 (13-74) vs. 20 (9-114) mg/dl] and ESR [44 (9-87) vs. 7 (1-30) mm/h] levels than controls, probably due to metabolic effects of inflammatory disease and corticotherapy.

Formato

text/html

Identificador

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822003000100001

Idioma(s)

en

Publicador

Sociedade Brasileira de Medicina Tropical - SBMT

Fonte

Revista da Sociedade Brasileira de Medicina Tropical v.36 n.1 2003

Palavras-Chave #Pemphigus foliaceus #Glucocorticoid therapy #Serum lipids #Triglycerides
Tipo

journal article