Severe Megaloblastic Anaemia in an Infant


Autoria(s): Rodrigues, V; Dias, A; Brito, MJ; Galvão, I; Cordeiro Ferreira, G
Data(s)

19/11/2013

19/11/2013

2011

Resumo

Vitamin B 12 or cobalamin deficiency, a rare clinical entity in pediatric age, is found most exclusively in breastfed infants, whose mothers are strictly vegetarian non-supplemented or with pernicious anaemia. In this article, the authors describe a 10-month-old infant admitted for vomiting, refusal to eat and prostration. The infant was exclusively breastfed and diffi culties in introduction of new foods were reported. Failure to thrive since 5 months of age was also noticed. Laboratory evaluation revealed severe normocytic normochromic anaemia and cobalamin defi cit. A diagnosis of α-thalassemia trait was also made. Maternal investigation showed autoimmune pernicious anaemia. This case shows the severity of vitamin B 12 deficiency and the importance of adopting adequate and precocious measures in order to prevent potentially irreversible neurologic damage.

Identificador

BMJ Case Reports 2011 May 16 ; doi:10.1136/bcr.02.2011.3835

http://hdl.handle.net/10400.17/1553

Idioma(s)

eng

Publicador

BMJ Publishing Group

Direitos

openAccess

Palavras-Chave #Vitamina B 12 #Anemia Megaloblástica #Criança #HDE PED
Tipo

article