Severe Megaloblastic Anaemia in an Infant
Data(s) |
19/11/2013
19/11/2013
2011
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Resumo |
Vitamin B 12 or cobalamin deficiency, a rare clinical entity in pediatric age, is found most exclusively in breastfed infants, whose mothers are strictly vegetarian non-supplemented or with pernicious anaemia. In this article, the authors describe a 10-month-old infant admitted for vomiting, refusal to eat and prostration. The infant was exclusively breastfed and diffi culties in introduction of new foods were reported. Failure to thrive since 5 months of age was also noticed. Laboratory evaluation revealed severe normocytic normochromic anaemia and cobalamin defi cit. A diagnosis of α-thalassemia trait was also made. Maternal investigation showed autoimmune pernicious anaemia. This case shows the severity of vitamin B 12 deficiency and the importance of adopting adequate and precocious measures in order to prevent potentially irreversible neurologic damage. |
Identificador |
BMJ Case Reports 2011 May 16 ; doi:10.1136/bcr.02.2011.3835 |
Idioma(s) |
eng |
Publicador |
BMJ Publishing Group |
Direitos |
openAccess |
Palavras-Chave | #Vitamina B 12 #Anemia Megaloblástica #Criança #HDE PED |
Tipo |
article |