Oxidative behaviour of apomorphine and its metabolites


Autoria(s): Garrido, Jorge; Delerue-Matos, Cristina; Borges, F.; Macedo, Tice R. A.; Oliveira-Brett, A. M.
Data(s)

25/11/2013

25/11/2013

2002

Resumo

The metabolism of apomorphine is quite complex due to interactions with proteins and other tissue components that affect its pharmacokinetic profile. The electrochemical oxidation mechanism of apomorphine and of some synthesised apomorphine derivatives was studied. It was found to be related to the reaction of o-diphenol and tertiary amine groups and strongly dependent on pH.

Identificador

http://dx.doi.org/10.1016/S1567-5394(01)00169-4

http://hdl.handle.net/10400.22/2944

Idioma(s)

eng

Publicador

Elsevier

Relação

Bioelectrochemistry; Vol.55, Issue 1-2

http://www.sciencedirect.com/science/article/pii/S1567539401001694#

Direitos

closedAccess

Palavras-Chave #Apomorphine #Oxidative behaviour #Electrochemistry
Tipo

article