Analysis of the interference of endogenous circadian rhythms on 3'- deoxy- 3'- [18F]Fluorothymidine physiological uptake at the human bone marrow
| Data(s) |
17/05/2013
17/05/2013
01/10/2011
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|---|---|
| Resumo |
The main purpose of the present study is to determine if the circadian rhythms present in the human bone marrow are likely to influence 3’- deoxy- 3’-[18F] Fluorothymidine (18F-FLT) uptake in the same organ. The 18F-FLT is a Thymidine analogous proliferation agent. The relatively high physiological uptake of this tracer in the bone marrow diminishes the Tumor/Background (T/B) ratio, decreasing the detection accuracy of PET/CT and possibly affecting SUV quantifications. |
| Identificador |
Varela NM, Lucena F, Carapinha MJ, Vieira L. Analysis of the interference of endogenous circadian rhythms on 3'- deoxy- 3'- [18F]Fluorothymidine physiological uptake at the human bone marrow. Eur j Nucl Med Mol Imaging. 2011;38(2 Suppl):S452. 1619-7089 |
| Idioma(s) |
eng |
| Publicador |
Springer |
| Relação |
http://link.springer.com/content/pdf/10.1007%2Fs00259-011-1913-y.pdf |
| Direitos |
openAccess |
| Palavras-Chave | #Nuclear medicine #Endogenous circadian rhythms #Human bone marrow #18F-Fluorothymidine |
| Tipo |
conferenceObject |
