Development of novel ionic liquids based on ampicillin


Autoria(s): Ferraz, Ricardo; Prudêncio, Cristina; Branco, Luís; Marrucho, Isabel; Araújo, João; Rebelo, Luís; Ponte, Manuel Nunes; Noronha, João Paulo; Petrovski, Zeljko
Data(s)

13/06/2013

13/06/2013

2012

Resumo

Novel ionic liquids containing ampicillin as an active pharmaceutical ingredient anion were prepared with good yields by using a new, efficient synthetic procedure based on the neutralization of a moderately basic ammonia solution of ampicillin with different organic cation hydroxides. The relevant physical and thermal properties of these novel ionic liquids based on ampicillin were also evaluated.

Identificador

DOI 10.1039/c2md00269h

http://hdl.handle.net/10400.22/1704

Idioma(s)

eng

Publicador

Med. Chem. Commun.

Direitos

openAccess

Tipo

article