Biological monitoring of aflatoxin (AFB1) in workers of swine and poultry production


Autoria(s): Viegas, Susana; Veiga, Luísa; Almeida, Ana; Figueiredo, Paula; Carolino, Elisabete; Viegas, Carla
Data(s)

14/11/2012

14/11/2012

01/06/2012

Resumo

Although a great body of literature exists concerning the ingestion of food contaminated with aflatoxin, there are still few studies regarding mycotoxin inhalation in occupational settings. Since mycotoxins are relatively non-volatile, inhalation exposure is cause by inhalation of airborne fungal particulates or fungi-contaminated substrates that contain aflatoxin. We intend to know if there is occupational exposure to aflatoxin in Portuguese poultry and swine production. A total of 19 individuals (11 swine; 8 poultry) agreed and provided blood samples during the course of this investigation. Measurement of AFB1 was performed by ELISA. The samples were treated with pronase (Merck), wash in a Column C18 and purification was made with immunoaffinity columns (R.biopharma), specific for AFB1. It was applied statistical test (Mann-Whitney) to verified statistical difference in AFB1 results between the two settings. Results varied with concentrations from <LOD to 5.96 ng ml-1 (Poultry: <LOD – 3.67 ng ml-1; Swine: <LOD -5.96 ng ml-1. There wasn’t found statistical difference between the two occupational settings, however, results reveal a tendency for poultry workers have higher aflatoxin values, probably because poultry activities are promoter of particles exposure. Only women’s in both settings have results <LOD. These results are probably due to differences in the activities performed. Exposure to air and dust containing aflatoxin by inhalation should be consider a route of exposure in both settings.

Identificador

Viegas S, Veiga L, Almeida A, Figueiredo P, Carolino E, Viegas C. Biological monitoring of aflatoxin (AFB1) in workers of swine and poultry production. Toxicol Lett. 2012;211 Suppl:S49.

0378-4274

http://hdl.handle.net/10400.21/1928

Idioma(s)

eng

Publicador

Elsevier

Relação

http://www.sciencedirect.com/science/article/pii/S0378427412003001

Direitos

openAccess

Palavras-Chave #Saúde ambiental #Saúde ocupacional #Aflatoxinas #Aviário #Environmental health #Occupational health #Aflatoxin B1 #Poultry #Biological monitoring #Swine production
Tipo

conferenceObject