Fiber average size and distribution dependence on the electrospinning parameters of poly(vinylidene fluoride trifluoroethylene)) membranes for biomedical applications
Data(s) |
17/08/2012
|
---|---|
Resumo |
Poly(vinylidene fluoride-trifluoethylene) electrospun membranes were obtained from a blend of dimethylformamide (DMF) and methylethylketone (MEK) solvents. The inclusion of the MEK to the solvent system promotes a faster solvent evaporation allowing complete polymer crystallization during the jet travelling between the tip and the grounded collector. Several processing parameters were systematically changed to study their influence on fiber dimensions. Applied voltage and inner needle diameter do not have large influence on the electrospun fiber average diameter but in the fiber diameter distribution. On the other hand, the increase of the distance between the needle tip to collector results in fibers with larger average diameter. Independently on the processing conditions, all mats are produced in the electroactive phase of the polymer. Further, MC-3T3-E1cell adhesion was not inhibited by the fiber mats preparation, indicating their potential use for biomedical applications. This work is funded by FEDER funds through the "Programa Operacional Factores de Competitividade – COMPETE" and by national funds arranged by FCT- Fundação para a Ciência e a Tecnologia, project references NANO/NMed-SD/0156/2007, PTDC/CTM/73030/2006 and PTDC/CTM/69316/2006. The authors also thank support from the COST Action MP1003, 2010 ‘European Scientific Network for Artificial Muscles’. V.S., V.C. and J.N.P thanks the FCT for the SFRH/BPD/63148/2009, SFRH/BD/48708/2008 and SFRH/BD/66930/2009, grants respectively. C. R. thanks the IINL for a financial support via a PhD. |
Formato |
application/pdf |
Identificador | |
Idioma(s) |
eng |
Publicador |
Applied Physics A |
Direitos |
info:eu-repo/semantics/openAccess |
Palavras-Chave | #Electroactive membranes #Electrospinning #Poly(vinylidene fluoride–trifluoroethylene) (P(VDF–TrFE)) #Tissue and biomedical engineering |
Tipo |
info:eu-repo/semantics/article |