Fetal Growth Spurt and Pregestational Diabetic Pregnancy


Autoria(s): Wong, S. F.; Oats, J.; Chan, F. Y.; McIntyre, D. H. D.
Data(s)

01/01/2002

Resumo

OBJECTIVE - To assess the timing of fetal growth spurt among pre-existing diabetic pregnancies (types 1 and 2) and its relationship with diabetic control. To correlate fetal growth acceleration with factors that might influence fetal growth. RESEARCH DESIGN AND METHODS - This retrospective study involved all pregestational diabetic pregnancies delivered at a tertiary obstetric hospital in Australia between 1 January 1994 and 31 December 1999. Pregnancies with major congenital fetal anomalies, multiple pregnancies, small-for-gestational-age pregnancies (90th centile for gestation) were compared with babies with normal birth weights. RESULTS- A total of 101 diabetic pregnancies were included. Diabetic mothers, who had LGA babies, had significantly higher prepregnancy body weight and BMI (P < 0.05). There were no differences in maternal age or parity among the two groups. There were also no differences in the first-, second-, and third-trimester HbA(1c) levels between the two groups. The abdominal circumference z-scores were significantly higher for LGA babies from 18 weeks and thereafter. The differences increased progressively as the gestation advanced. Maximum difference was noted in the third trimester (30-38 weeks). CONCLUSIONS - Fetal growth acceleration in LGA fetuses of diabetic mothers starts in the second trimester, from as early as 18 weeks. In this study, glucose control did not appear to have a direct effect on the incidence of LGA babies, and such observation might result from the effects of other confounding factors.

Identificador

http://espace.library.uq.edu.au/view/UQ:63797

Idioma(s)

eng

Publicador

American Diabetes Association

Palavras-Chave #Blood-glucose Control #Birth-weight #Glycemic Control #Macrosomia #Mellitus #Women #1st-trimester #Mothers #Fetus #C1 #321005 Fetal Development and Medicine #730116 Reproductive system and disorders
Tipo

Journal Article