Use of laser phototherapy on a delayed wound healing of oral mucosa previously submitted to radiotherapy: case report


Autoria(s): RAMALHO, Karen M.; LUIZ, Ana C.; EDUARDO, Carlos de Paula; TUNER, Jan; MAGALHAES, Roberto P.; MAGALHAES, Marina Gallottini
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

19/10/2012

19/10/2012

2011

Resumo

Radiotherapy produces both acute and delayed effects on mucosal tissues, disturbing their healing. This report shows a successful treatment with laser phototherapy (LPT) on a delayed wound healing in oral mucosa previously submitted to radiotherapy with a follow up of 3 years. A 47-year-old patient treated 6 months earlier for tongue squamous cell carcinoma by surgery and radiotherapy presented with a mass in the operated area. Biopsy showed chronic inflammatory infiltrate around a residual polyglactin suture. After 2 months there was a painful mucosal dehiscence on the biopsy site. LPT was performed using a semiconductor laser with 660-nm wavelength (InGaAlP) and spot size of 0.04 cm(2). The parameters applied were 40 mW, 4 Jcm(2)/point, 0.16 J/point, 2.4 J/session. The irradiation was performed punctually, through contact mode in 15 points (4 seconds/point), on top of and around the lesion, during ten sessions. The wound healed completely after ten sessions. This treatment proved to be conservative and effective, inducing healing of a chronic wound in a tissue previously submitted to radiotherapy.

Identificador

INTERNATIONAL WOUND JOURNAL, v.8, n.4, p.413-418, 2011

1742-4801

http://producao.usp.br/handle/BDPI/25635

10.1111/j.1742-481X.2011.00788.x

http://dx.doi.org/10.1111/j.1742-481X.2011.00788.x

Idioma(s)

eng

Publicador

WILEY-BLACKWELL

Relação

International Wound Journal

Direitos

restrictedAccess

Copyright WILEY-BLACKWELL

Palavras-Chave #Healing #Laser #Squamous cell carcinoma #LOW-INTENSITY LASER #HE-NE-LASER #HEMATOPOIETIC-CELL TRANSPLANTATION #IN-VITRO #IRRADIATION INCREASES #CULTURED FIBROBLASTS #PROLIFERATION RATE #RADIATION-THERAPY #TUMOR-CELLS #LEVEL
Tipo

article

original article

publishedVersion