Clonal Complex Chromosome Aberration in Non-Ossifying Fibroma


Autoria(s): BRASSESCO, Maria Sol; VALERA, Elvis Terci; ENGEL, Edgard Eduard; NOGUEIRA-BARBOSA, Marcello Henrique; BECKER, Aline Paixao; SCRIDELI, Carlos Alberto; TONE, Luiz Gonzaga
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

19/10/2012

19/10/2012

2010

Resumo

Cytogenetic information of non-ossifying fibromas (NOFs) is exceptionally limited. This fact relies, in part, on their benign nature but mainly because most cases evolve undetected or there is no need for surgical intervention. We report the case of a NOF arising in the left tibia of a 14-year-old male with an invariable clonal translocation. The karyotype was denoted as 42-46,XY,t(11;3;14)(q23;p21;p11). There are only two previous reported cases of clonally aberrant NOF. Records from additional cases will be essential to assess whether consistent karyotypic aberrations define this lesion. Pediatr Blood Cancer 2010;54:764 767. (C) 2010 Wiley-Liss, Inc.

FAPESP Fundacao de Amparo a Pesquisa do Estado de Sao Paulo[06/04827-3]

FAPESP Fundacao de Amparo a Pesquisa do Estado de Sao Paulo[07/54236-4]

Identificador

PEDIATRIC BLOOD & CANCER, v.54, n.5, p.764-767, 2010

1545-5009

http://producao.usp.br/handle/BDPI/25114

10.1002/pbc.22393

http://dx.doi.org/10.1002/pbc.22393

Idioma(s)

eng

Publicador

WILEY-LISS

Relação

Pediatric Blood & Cancer

Direitos

restrictedAccess

Copyright WILEY-LISS

Palavras-Chave #benign tumor #complex translocation #cytogenetics #non-ossifying fibroma #SQUAMOUS-CELL CARCINOMAS #NONOSSIFYING FIBROMA #CYTOGENETIC ANALYSIS #ABNORMALITIES #BONE #CHILDREN #TUMOR #Oncology #Hematology #Pediatrics
Tipo

article

original article

publishedVersion