TAGLN expression is deregulated in endometriosis and may be involved in cell invasion, migration, and differentiation


Autoria(s): HIDALGO, Gabriela dos Santos; MEOLA, Juliana; SILVA, Julio Cesar Rosa e; PAZ, Claudia Cristina Paro de; FERRIANI, Rui Alberto
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

19/10/2012

19/10/2012

2011

Resumo

We found an increased expression of the TAGLN gene in endometriotic lesions compared with the eutopic endometrium of the same patients by real-time polymerase chain reaction. It is possible that this deregulation contributes to the development and maintenance of endometriosis by being involved in the pathways of organization of cytoskeletal architecture. (Fertil Steril (R) 2011;96:700-3. (C)2011 by American Society for Reproductive Medicine.)

Amparo a Pesquisa do Estado de Sao Paulo (FAPESP), Sao Paulo, Brazil

Fundacao de Apoio ao Ensino, Pesquisa e Assistencia (FAEPA/HCFMRP-USP), Ribeirao Preto, Sao Paulo, Brazil

Identificador

FERTILITY AND STERILITY, v.96, n.3, p.700-703, 2011

0015-0282

http://producao.usp.br/handle/BDPI/24504

10.1016/j.fertnstert.2011.06.052

http://dx.doi.org/10.1016/j.fertnstert.2011.06.052

Idioma(s)

eng

Publicador

ELSEVIER SCIENCE INC

Relação

Fertility and Sterility

Direitos

restrictedAccess

Copyright ELSEVIER SCIENCE INC

Palavras-Chave #Cell differentiation #cell invasion #cell migration #endometriosis #gene expression #TAGLN #SMOOTH-MUSCLE-CELLS #EUTOPIC ENDOMETRIUM #EPITHELIAL-CELLS #GENE-EXPRESSION #PROSTATE-CANCER #PODOSOMES #PROTEIN #INVADOPODIA #TRANSGELIN #SM22 #Obstetrics & Gynecology #Reproductive Biology
Tipo

article

original article

publishedVersion