A pilot case-control association study of cytokine polymorphisms in Brazilian women presenting with HPV-related cervical lesions
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
19/10/2012
19/10/2012
2008
|
| Resumo |
Objective and study design: A case-control study was conducted on 42 Brazilian women presenting with human papilloma virus (HPV) infection and cervical lesion and 87 HPV-negative women to evaluate single nucleotide polymorphisms observed in TNF-alpha, TGF-beta, IL-10, IL-6, and IFN-gamma genes. Results and conclusion: No significant association was observed on the cytokine polymorphisms analyzed in this series. Larger studies using cytokine polymorphisms may be useful for providing further information regarding their influence or not in HPV-related cervical lesions. (C) 2008 Elsevier Ireland Ltd. All rights reserved. FAPESP[97/04490-8] FAPESP[01/02908-2] |
| Identificador |
European Journal of Obstetrics, Gynecology, and Reproductive Biology 0301-2115 http://producao.usp.br/handle/BDPI/24025 10.1016/j.ejogrb.2008.04.007 |
| Idioma(s) |
eng |
| Publicador |
ELSEVIER IRELAND LTD |
| Relação |
European Journal of Obstetrics, Gynecology, and Reproductive Biology |
| Direitos |
restrictedAccess Copyright ELSEVIER IRELAND LTD |
| Palavras-Chave | #Cytokines #Polymorphism #Cervical lesions #HPV #Brazilian women #HUMAN-PAPILLOMAVIRUS #GENE POLYMORPHISM #UTERINE CERVIX #CANCER #INFECTION #Obstetrics & Gynecology #Reproductive Biology |
| Tipo |
article original article publishedVersion |
