Routine abdominal drains after Roux-en-Y gastric bypass: a prospective evaluation of the inflammatory response
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
19/10/2012
19/10/2012
2010
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| Resumo |
Background: Despite the extensive published data regarding the use of drains in surgery, it is still controversial. Most bariatric surgeons use drains as routinely. However, drains have sometimes have been shown to be unhelpful and even to increase the anastomotic leak rates. The purpose of the present study was to evaluate the peritoneal inflammatory response in the presence of a drain left in place until the seventh postoperative day after bariatric surgery. Methods: All patients who underwent open Roux-en-Y gastric bypass from February 2007 to August 2008 were prospectively evaluated. A 24F Blake drain was left in place for 7 days. The peritoneal effluent from the drain was collected for the determination of cytokine levels and for microbiologic analysis. Results: A total of 107 obese patients were studied. A marked increase in the levels of tumor necrosis factor-alpha and interleukin-1 beta was observed by the seventh postoperative day, even in patients without any abdominal complications. Bacterial contamination of the peritoneal effluent was also demonstrated. Conclusion: The results of our study have shown that at 7 days after surgery, a marked peritoneal inflammatory response and bacterial contamination are present. These findings could have resulted from the use of the drain for 7 postoperative days. (Surg Obes Relat Dis 2010;6:648-652.) (C) 2010 American Society for Metabolic and Bariatric Surgery. All rights reserved. FAPESP Fundacao de Amparo a Pesquisa do Estado de Sao Paulo |
| Identificador |
SURGERY FOR OBESITY AND RELATED DISEASES, v.6, n.6, p.648-652, 2010 1550-7289 http://producao.usp.br/handle/BDPI/23859 10.1016/j.soard.2009.09.017 |
| Idioma(s) |
eng |
| Publicador |
ELSEVIER SCIENCE INC |
| Relação |
Surgery for Obesity and Related Diseases |
| Direitos |
restrictedAccess Copyright ELSEVIER SCIENCE INC |
| Palavras-Chave | #Drains #Bariatric surgery #Inflammatory response #Gastric bypass #INTRAABDOMINAL INFECTION #SECONDARY PERITONITIS #BARIATRIC SURGERY #TNF-ALPHA #INTERLEUKIN-6 #MANAGEMENT #Surgery |
| Tipo |
article original article publishedVersion |