Sudden unexpected death in an adolescent with epilepsy: All roads lead to the heart?
Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
---|---|
Data(s) |
19/10/2012
19/10/2012
2011
|
Resumo |
The incidence of sudden unexpected death in epilepsy (SUDEP) has been estimated from 0.5-1.4/1,000 person-years in people with treated epilepsy, and 9/1,000 person-years in candidates for epilepsy surgery. Potential risk factors for SUDEP include: age, early onset of epilepsy, duration of epilepsy, uncontrolled seizures, seizure type and winter temperatures. The arrythmogenic side-effect of antiepileptic drugs and seizures may increase the risk of SUDEP. In this report, we describe a patient with prolonged post-ictal tachycardia in EEG video recordings with a typical case of SUDEP: a 16-year-old boy with medically intractable complex partial seizures. Magnetic resonance imaging revealed left mesial temporal sclerosis. During non-invasive video-EEG monitoring, the patient presented a post-ictal heart rate increased for five hours. Two months after video-EEG, he died from SUDEP during a tonic-clonic secondary generalized seizure. The possibility of cardiac involvement in the pathogenesis of SUDEP has been suggested by many studies. Evaluation of this patient with EEG-video monitoring, including measurement of heart rate, contributed to an identification of ictal tachycardia that may have played a role in the SUDEP. Premature mortality seems to be increased in patients with epilepsy, and cardiac abnormalities may be a possible cause of SUDEP. (Cardiol J 2011; 18, 2: 194-196) FAPESP CInAPCe-FAPESP INCT/MCT CNPq |
Identificador |
CARDIOLOGY JOURNAL, v.18, n.2, p.194-196, 2011 1897-5593 |
Idioma(s) |
eng |
Publicador |
VIA MEDICA |
Relação |
Cardiology Journal |
Direitos |
restrictedAccess Copyright VIA MEDICA |
Palavras-Chave | #sudden death #epilepsy #EEG #heart #Cardiac & Cardiovascular Systems |
Tipo |
article original article publishedVersion |