Stretch Injuries of Skeletal Muscles: Experimental Study in Rats` Soleus Muscle


Autoria(s): PACHIONI, Celia Aparecida Stellutti; MAZZER, Nilton; BARBIERI, Claudio Henrique; CAMARGO, Marcela Regina de; FREGONESI, Cristina Elena Prado Teles; CARMO, Edna Maria do; NOZABIELLI, Andrea Jeanne Lourenco; MARTINELLI, Alessandra Rezende
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

19/10/2012

19/10/2012

2009

Resumo

The study aimed to verify the physiological injury behavior by stretching the soleus muscle of rats, using a noninvasive experimental model. Twenty-four rats were used and divided into three groups of eight animals: control group (A), group that performed tetanus followed by electrical stimulation and a sudden dorsiflexion of the left paw performed by a device equipped with a mechanism of muscle soleus rapid stretching (B); and a group that only received the tetanus (C). Three days later, the animals were killed, and the soleus muscle was resected and divided into three segments. Morphological changes indicative of muscle damage appeared in all three segments of group B. In a lesser degree, similar changes were also detected in muscles subjected to only tetanus. This model was effective; reproducing an injury similar to what occurs in human sports injuries.

Identificador

INTERNATIONAL JOURNAL OF MORPHOLOGY, v.27, n.4, p.1139-1146, 2009

0717-9502

http://producao.usp.br/handle/BDPI/23705

http://apps.isiknowledge.com/InboundService.do?Func=Frame&product=WOS&action=retrieve&SrcApp=EndNote&UT=000279048100029&Init=Yes&SrcAuth=ResearchSoft&mode=FullRecord

Idioma(s)

eng

Publicador

SOC CHILENA ANATOMIA

Relação

International Journal of Morphology

Direitos

openAccess

Copyright SOC CHILENA ANATOMIA

Palavras-Chave #Disease models #Animal #Rats #Skeletal muscle #Tetany #CONTRACTION-INDUCED INJURY #ECCENTRIC EXERCISE #LENGTHENING CONTRACTIONS #STRAIN #DAMAGE #FIBERS #MICE #FAILURE #BIOLOGY #DOMS #Anatomy & Morphology
Tipo

article

original article

publishedVersion