The frequency of human papillomavirus findings in normal oral mucosa of healthy people by PCR


Autoria(s): ESQUENAZI, David; BUSSOLOTI FILHO, Ivo; CARVALHO, Maria da Gloria da Costa; BARROS, Fernando Souza de
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

19/10/2012

19/10/2012

2010

Resumo

The human papillomavirus (HPV) is a DNA virus, which belongs to papillomaviridae family, being of low and high risk, which infect the skin and mucous membranes and can induce benign and malign tumor formation. In the oral mucosa they have been associated with oral papilloma, focal epithelial hyperplasia, leucoplakia and oral neoplasia. Aim: to study the frequency of HPV finding in oral mucosa of normal people. Materials and methods: Prospective study, cross-sectional cohort. One hundred volunteers, young adults, healthy, aged between 20 and 31 years, university students with no history, no complains, without oral or oropharyngeal lesions. They were submitted to a questionnaire with questions regarding HPV infection epidemiology. The samples were harvested by brushing and analyzed by PCR. Results: The results were negative for HPV in all samples. Conclusion: It seems we had high social and economical class individuals, with nutrition rich in carotenoyds and vitamin C, low smoking and alcohol consumption and heterosexual habits with predominant monogamy and regular use of condoms.

Identificador

Brazilian Journal of Otorhinolaryngology (Impresso), v.76, n.1, p.78-84, 2010

1808-8694

http://producao.usp.br/handle/BDPI/23144

http://apps.isiknowledge.com/InboundService.do?Func=Frame&product=WOS&action=retrieve&SrcApp=EndNote&UT=000293570000013&Init=Yes&SrcAuth=ResearchSoft&mode=FullRecord

Idioma(s)

eng

Publicador

ASSOC BRASILEIRA OTORRINOLARINGOLOGIA & CIRURGIA CERVICOFACIAL

Relação

Brazilian Journal of Otorhinolaryngology (Impresso)

Direitos

closedAccess

Copyright ASSOC BRASILEIRA OTORRINOLARINGOLOGIA & CIRURGIA CERVICOFACIAL

Palavras-Chave #mouth #papillomavirus infections #mouth mucosa #POLYMERASE-CHAIN-REACTION #SOUTHERN BLOT HYBRIDIZATION #SQUAMOUS-CELL CARCINOMAS #NATURAL-HISTORY #HPV INFECTIONS #RISK #DNA #PREVALENCE #TYPE-16 #CANCER
Tipo

article

original article

publishedVersion