Impact of short-term preconceptional exposure to particulate air pollution on treatment outcome in couples undergoing in vitro fertilization and embryo transfer (IVF/ET)
Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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Data(s) |
19/10/2012
19/10/2012
2010
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Resumo |
To assess the potential effects of short-term exposure to particulate air pollution during follicular phase on clinical, laboratory, and pregnancy outcomes of women undergoing IVF/ET. Retrospective cohort study of 400 first IVF/ET cycles of women exposed to ambient particulate matter during follicular phase. Particulate matter (PM) was categorized into quartiles (Q(1): a parts per thousand currency sign30.48 A mu g/m(3), Q(2): 30.49-42.00 A mu g/m(3), Q(3): 42.01-56.72 A mu g/m(3), and Q(4): > 56.72 A mu g/m(3)). Clinical, laboratory, or treatment variables were not affected by follicular phase PM exposure periods. Women exposed to Q(4) period during the follicular phase of conception cycles had a higher risk of miscarriage (odds ratio, 5.05; 95% confidence interval: 1.04-25.51) when compared to women exposed to Q(1-3) periods. Our results show an association between brief exposure to high levels of ambient PM during the preconceptional period and early pregnancy loss, although no effect of this exposure on clinical, laboratory, and treatment outcomes was observed. |
Identificador |
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, v.27, n.7, p.371-382, 2010 1058-0468 http://producao.usp.br/handle/BDPI/22767 10.1007/s10815-010-9419-2 |
Idioma(s) |
eng |
Publicador |
SPRINGER/PLENUM PUBLISHERS |
Relação |
Journal of Assisted Reproduction and Genetics |
Direitos |
restrictedAccess Copyright SPRINGER/PLENUM PUBLISHERS |
Palavras-Chave | #In vitro fertilization #Particulate air pollution #Embryo development #Implantation #Miscarriage #PREGNANCY RATES #SAO-PAULO #BIRTH #MICE #FERTILITY #DISEASE #ENVIRONMENT #CALIFORNIA #QUALITY #FUTURE #Genetics & Heredity #Obstetrics & Gynecology |
Tipo |
article original article publishedVersion |