Treatment of Resistant Obsessive-Compulsive Disorder With Ventral Capsular/Ventral Striatal Gamma Capsulotomy: A Pilot Prospective Study
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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| Data(s) |
19/10/2012
19/10/2012
2009
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| Resumo |
A subgroup of obsessive-compulsive disorder (OCD) patients remains refractory to conventional treatments. For them, a new stereotactic radiosurgery has been recently developed: the ventral capsular/ventral striatal (VC/VS) gamma capsulotomy. The authors aim to report efficacy and adverse events of VC/VS gamma capsulotomy. Five refractory OCD patients were selected. The authors assessed OCD, anxiety and depressive symptoms, and side effects pre- and postoperatively. Three patients (60%) met response criteria 48 months after surgery. Adverse effects were episodic and transient. Ventral capsular/ventral striatal gamma capsulotomy holds therapeutic promise, with few adverse effects. (The Journal of Neuropsychiatry and Clinical Neurosciences 2009; 21:381-392) FAPESP Fundacao de Amparo a Pesquisa do Estado de Sao Paulo FAPESP CNPq Conselho Nacional de Desenvolvimento Cientifico e Tecnologico[1999/08560-6] CNPq Conselho Nacional de Desenvolvimento Cientifico e Tecnologico[2005/55628-08] CNPq CNPq Brazilian Council for Scientific and Technological Development[305548/2005-0] |
| Identificador |
JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES, v.21, n.4, p.381-392, 2009 0895-0172 |
| Idioma(s) |
eng |
| Publicador |
AMER PSYCHIATRIC PUBLISHING, INC |
| Relação |
Journal of Neuropsychiatry and Clinical Neurosciences |
| Direitos |
restrictedAccess Copyright AMER PSYCHIATRIC PUBLISHING, INC |
| Palavras-Chave | #STEREOTACTIC ANTERIOR CAPSULOTOMY #REFRACTORY ANXIETY DISORDERS #SCALE #RELIABILITY #DEPRESSION #STRATEGIES #INVENTORY #VALIDITY #BEHAVIOR #ISSUES #Clinical Neurology #Neurosciences #Psychiatry |
| Tipo |
article original article publishedVersion |
