Left Atrial Function After Ablation for Paroxysmal Atrial Fibrillation


Autoria(s): RODRIGUES, Ana Clara Tude; SCANAVACCA, Mauricio I.; CALDAS, Marcia Azevedo; HOTTA, Viviane Tiemi; PISANI, Cristiano; SOSA, Eduardo A.; MATHIAS JR., Wilson
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

19/10/2012

19/10/2012

2009

Resumo

Radiofirequency ablation of the pulmonary veins has been used to treat patients with paroxysmal atrial fibrillation (AF), and atrial damage after ablation is an issue of concern. To evaluate left atrial function shortly and midterm after ablation, 33 consecutive patients with paroxysmal AF were studied at baseline, 24 hours, and >= 6 months after ablation. Patients in sinus rhythm with normal ventricular function were included in the study. Echocardiographic measurements of left atrial volumes (Simpson`s rule) and transmitral and tissue Doppler myocardial (A`) velocities at the septal and lateral mitral annulus were undertaken at each time. Left atrial emptying fraction (EF; maximal - minimal left atrial volume/maximal left atrial volume) was used to express left atrial function. After 8 +/- 2 months, 30 of 33 patients returned (23 men, age 53 +/- 13 years), and all except 2 were in sinus rhythm. Shortly after ablation, left atrial minimal volumes increased (from 30 +/- 15 to 35 +/- 15 ml; p = 0.02), with maximal volumes unchanged, resulting in decreased left atrial EF (from 47 +/- 8 to 40 +/- 7 ml; p <0.05). Tissue Doppler septal A` velocities also decreased (from 8.2 +/- 1.8 to 6.9 +/- 2.0 cm/s; p <0.05). However, after midterm follow-up, both left atrial EF and septal A` velocities had slightly increased compared with shortly after ablation, although left atrial volumes remained similar to baseline. Septal A` velocity changes paralleled left atrial EF both shortly (r = 0.46, p = 0.02) and at midterm after ablation (r = 0.47, p = 0.01). In conclusion, after radiofrequency ablation, patients with paroxysmal AF experienced an initial impairment in atrial function, with improvement at longer term follow-up. (C) 2009 Elsevier Inc. All rights reserved. (Am J Cardiol 2009;103: 395-398)

FAPESP Fundacao de Amparo a Pesquisa do Estado de Sao Paulo, Sao Paulo, Brazil

Identificador

AMERICAN JOURNAL OF CARDIOLOGY, v.103, n.3, p.395-398, 2009

0002-9149

http://producao.usp.br/handle/BDPI/21282

10.1016/j.amjcard.2008.09.094

http://dx.doi.org/10.1016/j.amjcard.2008.09.094

Idioma(s)

eng

Publicador

EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC

Relação

American Journal of Cardiology

Direitos

restrictedAccess

Copyright EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC

Palavras-Chave #ECHOCARDIOGRAPHY #SIZE #Cardiac & Cardiovascular Systems
Tipo

article

original article

publishedVersion