Synthesis of homoallylic oxygenated alpha-methylene-gamma-butyrolactones: a model for preparing biologically active natural lactones
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
19/10/2012
19/10/2012
2008
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| Resumo |
In this Letter we describe a 12% overall yield synthesis of a model for homoallylic oxygenated alpha-methylene-gamma-butyrolactones with relative stereochemistry defined by selective hydrogenation with Rh/Al(2)O(3). The synthesis was realized in 9 steps involving simple reactions. (C) 2008 Elsevier Ltd. All rights reserved. Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) Financiadora de Estudos e Projetos (FINEP) |
| Identificador |
TETRAHEDRON LETTERS, v.49, n.40, p.5770-5772, 2008 0040-4039 http://producao.usp.br/handle/BDPI/20734 10.1016/j.tetlet.2008.07.099 |
| Idioma(s) |
eng |
| Publicador |
PERGAMON-ELSEVIER SCIENCE LTD |
| Relação |
Tetrahedron Letters |
| Direitos |
closedAccess Copyright PERGAMON-ELSEVIER SCIENCE LTD |
| Palavras-Chave | #synthesis #natural products #alpha-methylene-gamma-butyrolactones #NF-KAPPA-B #ENANTIOSELECTIVE TOTAL-SYNTHESIS #SESQUITERPENE LACTONES #STEREOSELECTIVE-SYNTHESIS #NEURAL-NETWORKS #1,10-SECO-EUDESMANOLIDES #EXPRESSION #ERIOLANIN #Chemistry, Organic |
| Tipo |
article original article publishedVersion |
