Base-catalysed rearrangements of 5-oxodihydroisoxazoles


Autoria(s): Prager, RH; Williams, CM
Data(s)

01/01/1999

Resumo

Five distinct pathways for the reaction of isoxazol-5(2H)-ones with bases or nucleophiles have been reported, and are detailed herein. That investigated in greatest detail, and of greatest application in heterocyclic synthesis, is that of isoxazolones unsubstituted at C-3, in which the sequentially formed ketenimine, alpha-lactone and ketene may all react with a nucleophile.

Identificador

http://espace.library.uq.edu.au/view/UQ:36116

Idioma(s)

eng

Palavras-Chave #Chemistry, Organic #Annelated Pyrimidines #Chemistry #Amines #Isoxazol-5(2h)-ones #Ketenimines #Derivatives #Photolysis #Salt
Tipo

Journal Article