Karyometric Study of Placentas from Mice with Acute Infection by Different Strains of Trypanosoma cruzi


Autoria(s): SALA, Miguel Angel; LOPES, Ruberval Armando; ABRAHAO, Ana Amelia Carraro; MENEGUETTE, Cicero; ALBUQUERQUE, Sergio de; RIBEIRO, Rosa Domingues
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

19/10/2012

19/10/2012

2008

Resumo

The objective of this work was to evaluate karyometrically the alterations caused by different strains of Trypanosoma cruzi in the mouse placenta. Pregnant mice, 60-day old, were intraperitoneally inoculated with 2 x 10(5) bloodstream trypomastigotes of the Colombian, Y, Bolivia or RC strain of T. cruzi. There were observed clear differences in the karyometric alterations of the trophoblast giant cells and in the spongiotrophoblast cells. The results demonstrate that the Colombian and RC strains cause alterations both in the trophoblast giant cells and in the spongiotrophoblast cells, whereas the Y and Bolivia strains provoke alterations only in the trophoblast giant cells. It is possible concluding that each strain has its own characteristics and that, in spite of the similar type of transmission, it show differential nuances in the placental pathogenic process.

Identificador

INTERNATIONAL JOURNAL OF MORPHOLOGY, v.26, n.3, p.623-627, 2008

0717-9502

http://producao.usp.br/handle/BDPI/20268

http://apps.isiknowledge.com/InboundService.do?Func=Frame&product=WOS&action=retrieve&SrcApp=EndNote&UT=000265411500018&Init=Yes&SrcAuth=ResearchSoft&mode=FullRecord

Idioma(s)

spa

Publicador

SOC CHILENA ANATOMIA

Relação

International Journal of Morphology

Direitos

openAccess

Copyright SOC CHILENA ANATOMIA

Palavras-Chave #Experimental Chagas` disease #Trypanosoma cruzi #Mouse #Placenta #Karyometry #Anatomy & Morphology
Tipo

article

original article

publishedVersion