Evaluation of the antioxidant activity as an additional parameter to attain the functional quality of natural extracts


Autoria(s): MARQUELE-OLIVEIRA, Franciane; FONSECA, Yris M.; GEORGETTI, Sandra R.; VICENTINI, Fabiana T. M. C.; BRONZATI, Viviane; FONSECA, Maria J. V.
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

19/10/2012

19/10/2012

2008

Resumo

Due to differences in the functional quality of natural extracts, we have also faced differences in their effectiveness. So, it was intended to assess the antioxidant activity of natural extracts in order to attain their functional quality. It was observed that all the extracts (brown and green propolis, Ginkgo biloba and Isoflavin Beta (R)) and the standard used (quercetin) showed antioxidant activity in a dose-dependent manner with IC50 values ranging from 0.21 to 155.28 mu g mL(-1) (inhibition of lipid peroxidation and scavenging of the DPPH center dot assays). We observed a high correlation (r(2)= 0.9913) among the antioxidant methods; on the other hand, the antioxidant activity was not related to the polyphenol and flavonoid content. As the DPPH center dot assay is a fast method, presents low costs and even has a high correlation with other antioxidant methods, it could be applied as an additional parameter in the quality control of natural extracts.

Identificador

LATIN AMERICAN JOURNAL OF PHARMACY, v.27, n.3, p.325-332, 2008

0326-2383

http://producao.usp.br/handle/BDPI/20096

http://apps.isiknowledge.com/InboundService.do?Func=Frame&product=WOS&action=retrieve&SrcApp=EndNote&UT=000259667600001&Init=Yes&SrcAuth=ResearchSoft&mode=FullRecord

Idioma(s)

eng

Publicador

COLEGIO FARMACEUTICOS PROVINCIA DE BUENOS AIRES

Relação

Latin American Journal of Pharmacy

Direitos

restrictedAccess

Copyright COLEGIO FARMACEUTICOS PROVINCIA DE BUENOS AIRES

Palavras-Chave #antioxidant activity #lipid peroxidation #natural extracts #scavenging of DPPHu radicals #PROPOLIS #CHEMILUMINESCENCE #FORMULATIONS #Pharmacology & Pharmacy
Tipo

article

original article

publishedVersion