Evaluation of the antioxidant activity as an additional parameter to attain the functional quality of natural extracts
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
19/10/2012
19/10/2012
2008
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| Resumo |
Due to differences in the functional quality of natural extracts, we have also faced differences in their effectiveness. So, it was intended to assess the antioxidant activity of natural extracts in order to attain their functional quality. It was observed that all the extracts (brown and green propolis, Ginkgo biloba and Isoflavin Beta (R)) and the standard used (quercetin) showed antioxidant activity in a dose-dependent manner with IC50 values ranging from 0.21 to 155.28 mu g mL(-1) (inhibition of lipid peroxidation and scavenging of the DPPH center dot assays). We observed a high correlation (r(2)= 0.9913) among the antioxidant methods; on the other hand, the antioxidant activity was not related to the polyphenol and flavonoid content. As the DPPH center dot assay is a fast method, presents low costs and even has a high correlation with other antioxidant methods, it could be applied as an additional parameter in the quality control of natural extracts. |
| Identificador |
LATIN AMERICAN JOURNAL OF PHARMACY, v.27, n.3, p.325-332, 2008 0326-2383 |
| Idioma(s) |
eng |
| Publicador |
COLEGIO FARMACEUTICOS PROVINCIA DE BUENOS AIRES |
| Relação |
Latin American Journal of Pharmacy |
| Direitos |
restrictedAccess Copyright COLEGIO FARMACEUTICOS PROVINCIA DE BUENOS AIRES |
| Palavras-Chave | #antioxidant activity #lipid peroxidation #natural extracts #scavenging of DPPHu radicals #PROPOLIS #CHEMILUMINESCENCE #FORMULATIONS #Pharmacology & Pharmacy |
| Tipo |
article original article publishedVersion |