Prospects in Lyophilization of Bovine Pericardium
Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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Data(s) |
19/10/2012
19/10/2012
2009
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Resumo |
Almost 30 years after the introduction of heart valve prostheses patients worldwide are benefiting from the implant of these devices. Among the various types of heart valves, the ones made of treated bovine pericardium have become a frequently used replacement of the heart`s native valve. Lyophilization, also known as freeze-drying, is an extremely useful technique for tissue storage for surgical applications. This article gives a brief overview on the current bovine pericardium lyophilization development, including the chemical modification to improve physical-chemical characteristics and the advanced technologies used to guarantee a high-quality product. It was shown that lyophilization process can be successfully applied as a method of bovine pericardium preservation and also as a technological tool to prepare new materials obtained by chemical modification of native tissues. |
Identificador |
ARTIFICIAL ORGANS, v.33, n.3, p.221-229, 2009 0160-564X http://producao.usp.br/handle/BDPI/19793 10.1111/j.1525-1594.2009.00712.x |
Idioma(s) |
eng |
Publicador |
WILEY-BLACKWELL PUBLISHING, INC |
Relação |
Artificial Organs |
Direitos |
restrictedAccess Copyright WILEY-BLACKWELL PUBLISHING, INC |
Palavras-Chave | #Bovine pericardium #Heart valves #Freeze-drying #Raman spectroscopy #Thermal analysis #DIFFERENTIAL SCANNING CALORIMETRY #BIOPROSTHETIC HEART-VALVE #EPOXY COMPOUNDS #SHRINKAGE TEMPERATURE #COLLAGEN #TISSUE #GLUTARALDEHYDE #CALCIFICATION #RESOLUTION #HYDRATION #Engineering, Biomedical #Transplantation |
Tipo |
article original article publishedVersion |