Novel deoxy-selenylconduritols: chemoenzymatic synthesis and biological evaluation
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
19/10/2012
19/10/2012
2009
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| Resumo |
The first synthesis of two selenyldeoxycyclitols (4-bromo-2-phenylselenyl conduritol F and 6-phenylselenylconduritol F) is reported via a chemoenzymatic enantioselective route. The key step of the synthesis is the selenolysis of a vinyl epoxide. The new compounds were evaluated for their capacity to inhibit the growth of different microorganisms using a modification of the agar diffusion technique with thin layer chromatography plates as support. (C) 2009 Elsevier Ltd. All rights reserved. PEDECIBA ANII[FCE252] CNPq[300.613/2007-5] FAPESP[07/59404-2] |
| Identificador |
TETRAHEDRON-ASYMMETRY, v.20, n.23, p.2673-2676, 2009 0957-4166 http://producao.usp.br/handle/BDPI/19681 10.1016/j.tetasy.2009.11.004 |
| Idioma(s) |
eng |
| Publicador |
PERGAMON-ELSEVIER SCIENCE LTD |
| Relação |
Tetrahedron-asymmetry |
| Direitos |
restrictedAccess Copyright PERGAMON-ELSEVIER SCIENCE LTD |
| Palavras-Chave | #EFFICIENT SYNTHESIS #(-)-CONDURITOL C #CONDURITOL #CYCLITOLS #SELENIUM #CONDURAMINE #DERIVATIVES #HYDROLYSIS #EPOXIDES #ANALOGS #Chemistry, Inorganic & Nuclear #Chemistry, Organic #Chemistry, Physical |
| Tipo |
article original article publishedVersion |
