Ultrasound Irradiation Promoted Large-Scale Preparation in Aqueous Media and Antioxidant Activity of Azoles
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
19/10/2012
19/10/2012
2009
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| Resumo |
The scaled-up preparation of 1H-pyrazole, 1-phenylpyrazole and isoxazole via sonocatalysis is reported. The products were isolated in good yields in short time reaction. These compounds had been assayed for antioxidant activity by ORAC and DPPH methodologies. The results showed that only 1-phenylpyrazole presented good antioxidant activity compared with Trolox(R). FAPESP[06/58124-3] FAPESP[06/56315-6] Universidade de São Paulo - CEPEMA-USP (Centro de Capacitacao e Pesquisa em Meio-ambiente) CNPq[310472/2007-5] INCT-CNPq CAPES |
| Identificador |
LETTERS IN DRUG DESIGN & DISCOVERY, v.6, n.5, p.323-326, 2009 1570-1808 |
| Idioma(s) |
eng |
| Publicador |
BENTHAM SCIENCE PUBL LTD |
| Relação |
Letters in Drug Design & Discovery |
| Direitos |
closedAccess Copyright BENTHAM SCIENCE PUBL LTD |
| Palavras-Chave | #Green chemistry #Isoxazole #Pyrazole #Sonocatalysis #ORAC #DPPH #MICROWAVE-ASSISTED SYNTHESIS #CHEMISTRY #PYRAZOLES #CHLORIDES #WATER #Chemistry, Medicinal |
| Tipo |
article original article publishedVersion |
