Selectivity in reduction of natural furanoheliangolides with Stryker's reagent
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
17/04/2012
17/04/2012
2011
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| Resumo |
Reduction of the natural sesquiterpene lactones furanoheliangolides with Stryker's reagent is an effective process for producing eremantholides through a biomimetic pathway. Other reduction products are also formed. Oxygenated functions at C-15 of the furanoheliangolide produce an increase in the velocities of the reactions and reduce the chemoselectivity of the reagent. FAPESP CNPq Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) |
| Identificador |
ORGANIC & BIOMOLECULAR CHEMISTRY, v.9, n.17, p.6148-6153, 2011 1477-0520 http://producao.usp.br/handle/BDPI/14852 10.1039/c1ob05734k |
| Idioma(s) |
eng |
| Publicador |
ROYAL SOC CHEMISTRY |
| Relação |
Organic & Biomolecular Chemistry |
| Direitos |
closedAccess Copyright ROYAL SOC CHEMISTRY |
| Palavras-Chave | #SCHULTZ-BIP COMPOSITAE #NF-KAPPA-B #SESQUITERPENE LACTONES #CONJUGATE REDUCTION #(+)-EREMANTHOLIDE-A #STEREOCHEMISTRY #CONSTRUCTION #<(PH3P)CUH>6 #CYCLIZATION #INHIBITION #Chemistry, Organic |
| Tipo |
article original article publishedVersion |
