Exact time-dependent solutions for a self-regulating gene


Autoria(s): RAMOS, A. F.; INNOCENTINI, G. C. P.; HORNOS, J. E. M.
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

17/04/2012

17/04/2012

2011

Resumo

The exact time-dependent solution for the stochastic equations governing the behavior of a binary self-regulating gene is presented. Using the generating function technique to rephrase the master equations in terms of partial differential equations, we show that the model is totally integrable and the analytical solutions are the celebrated confluent Heun functions. Self-regulation plays a major role in the control of gene expression, and it is remarkable that such a microscopic model is completely integrable in terms of well-known complex functions.

Identificador

PHYSICAL REVIEW E, v.83, n.6, 2011

1539-3755

http://producao.usp.br/handle/BDPI/14573

10.1103/PhysRevE.83.062902

http://dx.doi.org/10.1103/PhysRevE.83.062902

Idioma(s)

eng

Publicador

AMER PHYSICAL SOC

Relação

Physical Review E

Direitos

restrictedAccess

Copyright AMER PHYSICAL SOC

Palavras-Chave #EXPRESSION #NOISE #CONSEQUENCES #BISTABILITY #REPRESSION #NETWORKS #ORIGINS #HEUN #Physics, Fluids & Plasmas #Physics, Mathematical
Tipo

article

original article

publishedVersion