Influence of alpha-tocopherol on the levels of serum anti-oxLDL antibodies


Autoria(s): SANIBAL, Elaine Abrão Assef; DAMASCENO, Nágila Raquel Teixeira; GIDLUND, Magnus Ake; TORRES, Elizabeth Aparecida Ferraz da Silva
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

15/04/2012

15/04/2012

2009

Resumo

Purpose - This paper aims to evaluate the association between the a-tocopherol with the levels of serum anti-oxLDL autoantibodies and the risk markers for cardiovascular disease. Design/methodology/approach - A normolipidemic control group (n=30) and a hypercholesterolemic group (n=33) were used. Plasma lipid profile (colorimetric method), anti-oxLDL autoantibodies (ELISA) and a-tocopherol (HPLC) were analysed. Findings - The a-tocopherol (ß=-0.714; p=0.001) is negatively associated with anti-oxLDL autoantibodies in serum and with other risk markers for cardiovascular disease (BMI, WC, total cholesterol, LDL-c) and positively associated with HDL-c. Originality/value - Oxidized low density lipoprotein (oxLDL) and their autoantibodies are increased in subjects with hypercholesterolemia. The a-tocopherol can influence the levels of serum anti-oxLDL autoantibodies

FAPESP

CNPq

PRONUT

Identificador

Nutrition and Food Science, London, v. 39, n. 1, p. 50-58, 2009

0034-6659

http://producao.usp.br/handle/BDPI/14133

10.1108/00346650910930824

www.emeraldinsight.com/0034-6659.htm

Idioma(s)

eng

Publicador

London

Relação

Nutrition and Food Science

Direitos

openAccess

Emerald

Palavras-Chave #Sangue #ANTICORPOS (IMUNOLOGIA;SANGUE) #BIOMARCADORES (IMUNOLOGIA;SANGUE) #DOENÇAS CARDIOVASCULARES (FATORES) #VITAMINA E (IMUNOLOGIA;SANGUE)
Tipo

article

original article

publishedVersion