[factors Impacting The Growth And Nutritional Status Of Cystic Fibrosis Patients Younger Than 10 Years Of Age Who Did Not Undergo Neonatal Screening.]
Contribuinte(s) |
UNIVERSIDADE DE ESTADUAL DE CAMPINAS |
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Data(s) |
01/02/2015
27/11/2015
27/11/2015
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Resumo |
The aim of this study was to evaluate by clinical and laboratory parameters how cystic fibrosis (CF) affects growth and nutritional status of children who were undergoing CF treatment but did not receive newborn screening. A historical cohort study of 52 CF patients younger than 10 years of age were followed in a reference center in Campinas, Southeast Brazil. Anthropometric measurements were abstracted from medical records until March/2010, when neonatal screening program was implemented. Between September/2009 and March/2010, parental height of the 52 CF patients were also measured. Regarding nutritional status, four patients had Z-scores ≤ -2 for height/age (H/A) and body mass index/age (BMI/A). The following variables were associated with improved H/A ratio: fewer hospitalizations, longer time from first appointment to diagnosis, longer time from birth to diagnosis and later onset of respiratory disease. Forced vital capacity [FVC(%)], forced expiratory flow between 25-75% of FVC [FEF25-75(%)], forced expiratory volume in the first second [FEV1(%)], gestational age, birth weight and early respiratory symptoms were associated with IMC/A. Greater number of hospitalizations, diagnosis delay and early onset of respiratory disease had a negative impact on growth. Lower spirometric values, lower gestational age, lower birth weight, and early onset of respiratory symptoms had negative impact on nutritional status. Malnutrition was observed in 7.7% of cases, but 23% of children had nutritional risk. |
Identificador |
Revista Paulista De Pediatria : Orgao Oficial Da Sociedade De Pediatria De Sao Paulo. , 2015-Feb. 1984-0462 10.1016/j.rpped.2014.11.004 http://www.ncbi.nlm.nih.gov/pubmed/25681074 http://repositorio.unicamp.br/jspui/handle/REPOSIP/202121 25681074 |
Idioma(s) |
por |
Relação |
Revista Paulista De Pediatria : Orgao Oficial Da Sociedade De Pediatria De Sao Paulo Rev Paul Pediatr |
Direitos |
aberto Copyright © 2014 Associação de Pediatria de São Paulo. Publicado por Elsevier Editora Ltda. All rights reserved. |
Fonte |
PubMed |
Palavras-Chave | #Anthropometry #Antropometria #Child #Criança #Cystic Fibrosis/complications #Estado Nutricional #Fibrose Cística/complicações #Neonatal Screening #Nutritional Status #Triagem Neonatal |
Tipo |
Artigo de periódico |