Risk Of Leukemia In First Degree Relatives Of Patients With Nonsyndromic Cleft Lip And Palate.


Autoria(s): Gonçalves, Eduardo; Martelli, Daniella Reis Barbosa; Coletta, Ricardo Della; Vieira, Alexandre Rezende; Caldeira, Antônio Prates; Martelli, Hercílio
Contribuinte(s)

UNIVERSIDADE DE ESTADUAL DE CAMPINAS

Data(s)

27/11/2015

27/11/2015

Resumo

The aim of this study was to determine the frequency of leukemia in parents of patients with nonsyndromic cleft lip and/or cleft palate (NSCL/P). This case-control study evaluated first-degree family members of 358 patients with NSCL/P and 1,432 subjects without craniofacial alterations or syndromes. Statistical analysis was carried out using Fisher's test. From the 358 subjects with NSCL/P, 3 first-degree parents had history of leukemia, while 2 out of 1,432 subjects from the unaffected group had a family history of leukemia. The frequency of positive family history of leukemia was not significantly increased in first-degree relatives of patients with NSCL/P.

28

1-3

Identificador

Brazilian Oral Research. v. 28, n. 1, p. 1-3

1807-3107

http://www.ncbi.nlm.nih.gov/pubmed/25337933

http://repositorio.unicamp.br/jspui/handle/REPOSIP/201818

25337933

Idioma(s)

eng

Relação

Brazilian Oral Research

Braz Oral Res

Direitos

aberto

Fonte

PubMed

Palavras-Chave #Adolescent #Brazil #Case-control Studies #Cleft Lip #Cleft Palate #Family #Female #Humans #Leukemia #Male #Risk Factors
Tipo

Artigo de periódico