Stereoselective Synthesis Of Aryl Cyclopentene Scaffolds By Heck-matsuda Desymmetrization Of 3-cyclopentenol.
| Contribuinte(s) |
UNIVERSIDADE DE ESTADUAL DE CAMPINAS |
|---|---|
| Data(s) |
01/10/2014
27/11/2015
27/11/2015
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| Resumo |
A new enantioselective Heck-Matsuda desymmetrization reaction was accomplished by using 3-cyclopentenol to produce chiral five-membered 4-aryl cyclopentenol scaffolds in good yields and high ee's, together with some 3-aryl-cyclopentanones as minor products. Mechanistically, the hydroxyl group of 3-cyclopentenol acts as a directing group and is responsible for the cis- arrangement in the formation of the 4-aryl-cyclopentenols. 20 13117-21 |
| Identificador |
Chemistry (weinheim An Der Bergstrasse, Germany). v. 20, n. 41, p. 13117-21, 2014-Oct. 1521-3765 10.1002/chem.201404159 http://www.ncbi.nlm.nih.gov/pubmed/25155478 http://repositorio.unicamp.br/jspui/handle/REPOSIP/201658 25155478 |
| Idioma(s) |
eng |
| Relação |
Chemistry (weinheim An Der Bergstrasse, Germany) Chemistry |
| Direitos |
fechado © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
| Fonte |
PubMed |
| Palavras-Chave | #Heck Reaction #Aryldiazonium Salts #Chiral N,n Ligands #Desymmetrization #Palladium |
| Tipo |
Artigo de periódico |
