Cloning and expression in Escherichia coli of full-length complementary DNA coding for human α1-antitrypsin
| Data(s) |
15/06/2015
15/06/2015
1983
|
|---|---|
| Identificador |
0198-0238 AUT: ACR00659; |
| Idioma(s) |
eng |
| Relação |
P-008-R6M |
| Direitos |
restrictedAccess |
| Tipo |
article |
| Resumo |
A cDNA library prepared from human liver was screened for α₁-antitrypsin, a major constituent of plasma which functions as inhibitor of proteolytic enzyms. The library was screened using a 12-base-long synthetic oligodeoxyribonucleotide corresponding to a known DNA fragment of human α₁-antitrypsin and by hybrid-selection of α₁-antitrypsin mRNA. |
