Prevotella denticola Lipopolysaccharide from a Cystic Fibrosis Isolate Possesses a Unique Chemical Structure
| Data(s) |
23/03/2016
|
|---|---|
| Resumo |
<p>We report the first complete structural characterization of the lipopolysaccharide (LPS) from a cystic fibrosis (CF) clinical isolate of Prevotella denticola (B003V1S1X). Chemical, spectroscopic, and spectrometric analyses revealed a unique rough-type LPS (LOS) structure. The structure has a highly negatively charged heptasaccharide core region containing hexoses, with the first two sugars, 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) and mannose, highly phosphorylated. Furthermore, the lipid A moiety has the typical structure for the genus Prevotella, and was also highly phosphorylated.</p> |
| Identificador |
http://dx.doi.org/10.1002/ejoc.201600037 http://www.scopus.com/inward/record.url?scp=84959257307&partnerID=8YFLogxK |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Di Lorenzo , F , Silipo , A , Matier , T , Hanuszkiewicz , A , Elborn , J S , Lanzetta , R , Sturiale , L , Scamporrino , A , Garozzo , D , Valvano , M A , Tunney , M M & Molinaro , A 2016 , ' Prevotella denticola Lipopolysaccharide from a Cystic Fibrosis Isolate Possesses a Unique Chemical Structure ' European Journal of Organic Chemistry , vol 2016 , no. 9 , pp. 1732-1738 . DOI: 10.1002/ejoc.201600037 |
| Palavras-Chave | #Bacteria #Carbohydrates #NMR spectroscopy #Oligosaccharides #Structure elucidation #/dk/atira/pure/subjectarea/asjc/1600/1605 #Organic Chemistry #/dk/atira/pure/subjectarea/asjc/1600/1606 #Physical and Theoretical Chemistry |
| Tipo |
article |
