IGF-Binding Protein 2 - Oncogene or Tumor Suppressor?
| Data(s) |
01/02/2015
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|---|---|
| Resumo |
The role of insulin-like growth factor binding protein 2 (IGFBP2) in cancer is unclear. In general, IGFBP2 is considered to be oncogenic and its expression is often observed to be elevated in cancer. However, there are a number of conflicting reports in vitro and in vivo where IGFBP2 acts in a tumor suppressor manner. In this mini-review, we discuss the factors influencing the variation in IGFBP2 expression in cancer and our interpretation of these findings. |
| Formato |
application/pdf |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/openAccess |
| Fonte |
Pickard , A & McCance , D J 2015 , ' IGF-Binding Protein 2 - Oncogene or Tumor Suppressor? ' Frontiers in endocrinology , vol 6 , no. 25 , pp. 25 . DOI: 10.3389/fendo.2015.00025 |
| Tipo |
article |
