Rejection of the second allogeneic graft in a patient with severe aplastic anemia reversed by antilymphocyte globulin and donor lymphocyte infusions
Data(s) |
01/12/1996
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Resumo |
<p>Rejection after allogeneic BMT for aplastic anemia is a complication with a high risk of mortality. We describe a patient who, following a second episode of rejection after a second BMT entered a third durable remission subsequent to treatment with ALG, donor lymphocyte infusions, GM-CSF, and erythropoietin. Therapy was well tolerated. At 5 years after rejection treatment, his hematopoiesis is of complete donor origin as determined by analyses of short tandem repeats. Thus, donor lymphocyte infusions can be considered as a therapy option for marrow rejection after allogeneic BMT for aplastic anemia.</p> |
Identificador | |
Idioma(s) |
eng |
Direitos |
info:eu-repo/semantics/restrictedAccess |
Fonte |
Ljungman , P , Lawler , M , Lönnqvist , B , Ringdén , O , Shanwell , A & Lawler , M 1996 , ' Rejection of the second allogeneic graft in a patient with severe aplastic anemia reversed by antilymphocyte globulin and donor lymphocyte infusions ' Bone Marrow Transplantation , vol 18 , no. 6 , pp. 1179-81 . |
Palavras-Chave | #Adult #Anemia, Aplastic #Antilymphocyte Serum #Bone Marrow Transplantation #Cyclosporine #Erythropoietin #Graft Rejection #Granulocyte-Macrophage Colony-Stimulating Factor #Humans #Immunosuppression #Immunosuppressive Agents #Lymphocyte Transfusion #Male #Microsatellite Repeats #Polymerase Chain Reaction #Remission Induction #Transplantation, Homologous |
Tipo |
article |