Impact of an enhanced antibiotic stewardship on reducing methicillin-resistant Staphylococcus aureus in primary and secondary healthcare settings


Autoria(s): Aldeyab, M. A.; Scott, M. G.; Kearney, M. P.; Alahmadi, Y. M.; Magee, F. A.; Conlon, G.; McElnay, J. C.
Data(s)

01/03/2014

Resumo

<p>The objective of this study was to evaluate the impact of restricting high-risk antibiotics on methicillin-resistant Staphylococcus aureus (MRSA) incidence rates in a hospital setting. A secondary objective was to assess the impact of reducing fluoroquinolone use in the primary-care setting on MRSA incidence in the community. This was an interventional, retrospective, ecological investigation in both hospital and community (January 2006 to June 2010). Segmented regression analysis of interrupted time-series was employed to evaluate the intervention. The restriction of high-risk antibiotics was associated with a significant change in hospital MRSA incidence trend (coefficient=-0·00561, P=0·0057). Analysis showed that the intervention relating to reducing fluoroquinolone use in the community was associated with a significant trend change in MRSA incidence in community (coefficient=-0·00004, P=0·0299). The reduction in high-risk antibiotic use and fluoroquinolone use contributed to both a reduction in incidence rates of MRSA in hospital and community (primary-care) settings. </p>

Identificador

http://pure.qub.ac.uk/portal/en/publications/impact-of-an-enhanced-antibiotic-stewardship-on-reducing-methicillinresistant-staphylococcus-aureus-in-primary-and-secondary-healthcare-settings(ffb29e6a-e493-43e1-b2d6-b651d59cae72).html

http://dx.doi.org/10.1017/S0950268813001374

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Aldeyab , M A , Scott , M G , Kearney , M P , Alahmadi , Y M , Magee , F A , Conlon , G & McElnay , J C 2014 , ' Impact of an enhanced antibiotic stewardship on reducing methicillin-resistant Staphylococcus aureus in primary and secondary healthcare settings ' Epidemiology and Infection , vol 142 , no. 3 , pp. 494-500 . DOI: 10.1017/S0950268813001374

Palavras-Chave #Antibiotic stewardship #Fluoroquinolones #Interrupted-time series #Methicillin-resistant Staphylococcus aureus #Primary and secondary care #/dk/atira/pure/subjectarea/asjc/2700/2725 #Infectious Diseases #/dk/atira/pure/subjectarea/asjc/2700/2713 #Epidemiology
Tipo

article