Total colonic dye-spray increases the detection of diminutive adenomas during routine colonoscopy:a randomized controlled trial


Autoria(s): Brooker, JC; Saunders, BP; Shah, SG; Thapar, CJ; Thomas, HJW; Atkin, WS; Cardwell, CR; Williams, CB
Data(s)

01/09/2002

Resumo

<p>Background: Small adenomas may be missed during colonoscopy, but chromoscopy has been reported to enhance detection. The aim of this randomized-controlled trial was to determine the effect of total colonic dye spray on adenoma detection during routine colonoscopy.</p><p>Methods: Consecutive outpatients undergoing routine colonoscopy were randomized to a dye-spray group (0.1% indigo carmine used to coat the entire colon during withdrawal from the cecum) or control group (no dye).</p><p>Results: Two hundred fifty-nine patients were randomized, 124 to the dye-spray and 135 to the control group; demographics, indication for colonoscopy, and quality of the preparation were similar between the groups. Extubation from the cecum took a median of 9:05 minutes (range: 2:4824:44 min) in the dye-spray group versus 4:52 minutes (range: 1:42-15:21 min] in the control group (p <0.0001). The proportion of patients with at least 1 adenoma and the total number of adenomas were not different between groups. However, in the dye-spray group significantly more diminutive adenomas (</p><p>Conclusions: Dye-spray increases the detection of small adenomas in the proximal colon and patients with multiple adenomas, but long-term outcomes should be studied to determine the clinical value of these findings.</p>

Identificador

http://pure.qub.ac.uk/portal/en/publications/total-colonic-dyespray-increases-the-detection-of-diminutive-adenomas-during-routine-colonoscopy(3d354459-e9df-4656-8aad-509b74e3f25c).html

http://dx.doi.org/10.1067/mge.2002.126908

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Brooker , J C , Saunders , B P , Shah , S G , Thapar , C J , Thomas , H J W , Atkin , W S , Cardwell , C R & Williams , C B 2002 , ' Total colonic dye-spray increases the detection of diminutive adenomas during routine colonoscopy : a randomized controlled trial ' Gastrointestinal Endoscopy , vol 56 , no. 3 , pp. 333-338 . DOI: 10.1067/mge.2002.126908

Palavras-Chave #COLORECTAL-CANCER #MISS RATES #POLYPS #CHROMOSCOPY #POLYPECTOMY #DIAGNOSIS #LESIONS
Tipo

article