All-Cause Mortality up to and After Coronary Heart Disease and Stroke Events in European Middle-Aged Men The PRIME Study


Autoria(s): Majed, Bilal; Montaye, Michele; Wagner, Aline; Arveiler, Dominique; Ducimetiere, Pierre; Tafflet, Muriel; Ferrieres, Jean; Ruidavets, Jean-Bernard; Kee, Frank; Evans, Alun; Amouyel, Philippe; Prugger, Christof; Empana, Jean-Philippe
Data(s)

01/05/2015

Resumo

<p>Background and Purpose-The aim was to investigate prospectively the all-cause mortality risk up to and after coronary heart disease (CHD) and stroke events in European middle-aged men.</p><p>Methods-The study population comprised 10 424 men 50 to 59 years of age recruited between 1991 and 1994 in France (N=7855) and Northern Ireland (N=2747) within the Prospective Epidemiological Study of Myocardial Infarction. Incident CHD and stroke events and deaths from all causes were prospectively registered during the 10-year follow-up. In Cox's proportional hazards regression analysis, CHD and stroke events during follow-up were used as time-dependent covariates.</p><p>Results-A total of 769 CHD and 132 stroke events were adjudicated, and 569 deaths up to and 66 after CHD or stroke occurred during follow-up. After adjustment for study country and cardiovascular risk factors, the hazard ratios of all-cause mortality were 1.58 (95% confidence interval 1.18-2.12) after CHD and 3.13 (95% confidence interval 1.98-4.92) after stroke.</p><p>Conclusions-These findings support continuous efforts to promote both primary and secondary prevention of cardiovascular disease.</p>

Identificador

http://pure.qub.ac.uk/portal/en/publications/allcause-mortality-up-to-and-after-coronary-heart-disease-and-stroke-events-in-european-middleaged-men-the-prime-study(bb3f06a4-f79b-4782-a99f-26c2b5539365).html

http://dx.doi.org/10.1161/STROKEAHA.115.008903

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Majed , B , Montaye , M , Wagner , A , Arveiler , D , Ducimetiere , P , Tafflet , M , Ferrieres , J , Ruidavets , J-B , Kee , F , Evans , A , Amouyel , P , Prugger , C & Empana , J-P 2015 , ' All-Cause Mortality up to and After Coronary Heart Disease and Stroke Events in European Middle-Aged Men The PRIME Study ' Stroke , vol 46 , no. 5 , pp. 1371-1373 . DOI: 10.1161/STROKEAHA.115.008903

Palavras-Chave #cardiovascular disease #epidemiology #prevention #survival analysis #POPULATION
Tipo

article