THE SYNTHESIS OF BRIDGED-RING CARBOCYCLES AND HETEROCYCLES VIA PALLADIUM CATALYZED REGIOSPECIFIC CYCLIZATION REACTIONS
| Data(s) |
25/11/1991
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| Resumo |
<p>A catalyst system comprising 10 mol % (Pd(OAc) and 20 mol % PPh3 effects the cyclisation of aryl halides onto proximate alkenes via 5-, 6-, and 7-exo-trig, and 7-endo-trig processes giving a variety of bridged-ring carbo- and hetero-cycles in excellent yield. Double bond isomerisation in the product is rarely encountered and may be suppressed by the addition of Tl(1) salts. One example of diastereospecific bis-cyclisation is given and the crystal structure of 1-aza-2-sulphonyl-3,4-benzobicyclo[3.2.1]nona-6-ene is reported.</p> |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
GRIGG , R , SANTHAKUMAR , N V , SRIDHARAN , S , STEVENSON , P , TEASDALE , A , THORNTONPETT , M & WORAKUN , T 1991 , ' THE SYNTHESIS OF BRIDGED-RING CARBOCYCLES AND HETEROCYCLES VIA PALLADIUM CATALYZED REGIOSPECIFIC CYCLIZATION REACTIONS ' Tetrahedron , vol 47 , no. 46 , pp. 9703-9720 . |
| Palavras-Chave | #PALLADIUM CATALYSIS #BRIDGED-RING CYCLIZATION #METAL-PROMOTED CYCLIZATION #ANION CAPTURE PROCESSES #POLYENE CYCLIZATIONS #CRYSTAL-STRUCTURE #SILVER-NITRATE #ARYLATION #VINYLATION #COMPLEXES #HALIDES #ALKENES |
| Tipo |
article |
