ASYMMETRIC-SYNTHESIS OF S-(+)-4-AMINO-5-HEXYNOIC ACID


Autoria(s): MCALONAN, H; STEVENSON, PJ; Stevenson, Paul
Data(s)

01/01/1995

Resumo

<p>4-Amino-5-hexynoic acid is efficiently synthesised in eight steps (overall yield 10%) from commercially available (S)-glutamic acid. The key step was conversion of an aldehyde to an acetylene using diethylmethydiazophosphonate.</p>

Identificador

http://pure.qub.ac.uk/portal/en/publications/asymmetricsynthesis-of-s4amino5hexynoic-acid(eadcc1aa-843f-401d-905a-8808f0a40914).html

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

MCALONAN , H , STEVENSON , P J & Stevenson , P 1995 , ' ASYMMETRIC-SYNTHESIS OF S-(+)-4-AMINO-5-HEXYNOIC ACID ' Tetrahedron-Asymmetry , vol 6 , no. 1 , pp. 239-244 .

Palavras-Chave #GABA #AMINOTRANSFERASE #INHIBITORS #DERIVATIVES #MECHANISM #REAGENT
Tipo

article