Perifosine inhibits growth of human experimental endometrial cancers by blockade of AKT phosphorylation
| Data(s) |
01/11/2008
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| Resumo |
Perifosine is an orally active alkylphospholipid analog, which has shown anti-tumor activity in a variety of cancers by inhibition of AKT phosphorylation. The objective of the current study was to evaluate its efficacy in in vitro models of human endometrial cancer. |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Engel , J B , Honig , A , Schönhals , T , Weidler , C , Häusler , S , Krockenberger , M , Grunewald , T G , Dombrowski , Y , Rieger , L , Dietl , J & Wischhusen , J 2008 , ' Perifosine inhibits growth of human experimental endometrial cancers by blockade of AKT phosphorylation ' European journal of obstetrics, gynecology, and reproductive biology , vol 141 , no. 1 , pp. 64-9 . DOI: 10.1016/j.ejogrb.2008.06.007 |
| Palavras-Chave | #Antineoplastic Agents #Antineoplastic Combined Chemotherapy Protocols #Apoptosis #Cell Line, Tumor #Cisplatin #Endometrial Neoplasms #Female #Humans #Phosphorylation #Phosphorylcholine #Proto-Oncogene Proteins c-akt |
| Tipo |
article |
